Bibliographic Details
| Title: |
Clinical significance of substrate characteristics and ablation outcomes in patients with atrial fibrillation and significant functional mitral regurgitation |
| Authors: |
Jose Antonio L. Bautista, Chin-Yu Lin, Chi-Ting Lu, Li-Wei Lo, Yenn-Jiang Lin, Shih-Lin Chang, Yu-Feng Hu, Fa-Po Chung, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Ting-Yung Chang, Ling Kuo, Chih-Min Liu, Shin-Huei Liu, Cheng-I Wu, Ming-Jen Kuo, Guan-Yi Li, Yu-Shan Huang, Shang-Ju Wu, Yoon Kee Siow, Ngoc Nguyen Dinh Son, Dat Cao Tran, Shih-Ann Chen |
| Source: |
Frontiers in Cardiovascular Medicine, Vol 10 (2023) |
| Publisher Information: |
Frontiers Media S.A., 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| Subject Terms: |
atrial fibrillation, mitral regurgitation, substrate, ablation, echocardiography atrial fibrillation, catheter ablation, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| More Details: |
BackgroundAtrial fibrillation (AF) and mitral regurgitation (MR) have a complex interplay. Catheter ablation (CA) of AF may be a potential method to improve the severity of MR in AF patients.MethodsPatients with symptomatic AF and moderate to severe MR who underwent catheter ablation from 2011 to 2021 were retrospectively included in the study. Patients' baseline characteristics and electrophysiological features were examined. These patients were classified as group 1 with improved MR and group 2 with refractory MR after CA.ResultsFifty patients (age 60.2 ± 11.6 years, 29 males) were included in the study (32 in group 1 and 18 in group 2). Group 1 patients had a lower CHA2DS2-VASc score (1.7 ± 1.5 vs. 2.7 ± 1.5, P = 0.005) and had a lower incidence of hypertension (28.1% vs. 66.7%, P = 0.007) and diabetes mellitus (3.1% vs. 22.2%, P = 0.031) as compared to group 2 patients. Electroanatomic three-dimensional (3D) mapping showed that group 1 patients demonstrated less scars on the posterior bottom of the left atrium compared to group 2 patients (12.5% vs. 66.7%, P |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2297-055X |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fcvm.2023.1265890/full; https://doaj.org/toc/2297-055X |
| DOI: |
10.3389/fcvm.2023.1265890 |
| Access URL: |
https://doaj.org/article/082cdee4c24a429c91e35fbad961ad93 |
| Accession Number: |
edsdoj.082cdee4c24a429c91e35fbad961ad93 |
| Database: |
Directory of Open Access Journals |
