Bibliographic Details
| Title: |
Systematic analysis reveals the prevalence and principles of bypassable gene essentiality |
| Authors: |
Jun Li, Hai-Tao Wang, Wei-Tao Wang, Xiao-Ran Zhang, Fang Suo, Jing-Yi Ren, Ying Bi, Ying-Xi Xue, Wen Hu, Meng-Qiu Dong, Li-Lin Du |
| Source: |
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
| Publisher Information: |
Nature Portfolio, 2019. |
| Publication Year: |
2019 |
| Collection: |
LCC:Science |
| Subject Terms: |
Science |
| More Details: |
An essential gene may become non-essential when another gene is mutated. Here, the authors investigate this type of digenic interaction, termed ‘bypass of essentiality’, in the fission yeast Schizosaccharomyces pombe, and show that bypassable essential genes are common and share certain features. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-019-08928-1 |
| Access URL: |
https://doaj.org/article/081d51e49b2e42a4b1235dc234b85b81 |
| Accession Number: |
edsdoj.081d51e49b2e42a4b1235dc234b85b81 |
| Database: |
Directory of Open Access Journals |
