Bibliographic Details
| Title: |
Serum levels of neurotensin, pannexin-1, and sestrin-2 and the correlations with sleep quality or/and cognitive function in the patients with chronic insomnia disorder |
| Authors: |
Ai-Xi Su, Zi-Jie Ma, Zong-Yin Li, Xue-Yan Li, Lan Xia, Yi-Jun Ge, Gui-Hai Chen |
| Source: |
Frontiers in Psychiatry, Vol 15 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Psychiatry |
| Subject Terms: |
cognition, insomnia disorder, neurotensin, pannexin-1, sestrin-2, Psychiatry, RC435-571 |
| More Details: |
ObjectivesTo examine serum concentrations of neurotensin, pannexin-1 and sestrin-2, and their correlations with subjective and objective sleep quality and cognitive function in the patients with chronic insomnia disorder (CID).MethodsSixty-five CID patients were enrolled continuously and fifty-six good sleepers in the same period were served as healthy controls (HCs). Serum levels of neurotensin, pannexin-1 and sestrin-2 were measured by enzyme-linked immunosorbent assays. Sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI) and polysomnography, and mood was evaluated by 17-item Hamilton Depression Rating Scale. General cognitive function was assessed with the Chinese-Beijing Version of Montreal Cognitive Assessment and spatial memory was evaluated by Blue Velvet Arena Test (BVAT).ResultsRelative to the HCs, the CID sufferers had higher levels of neurotensin (t=5.210, p |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1664-0640 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fpsyt.2024.1360305/full; https://doaj.org/toc/1664-0640 |
| DOI: |
10.3389/fpsyt.2024.1360305 |
| Access URL: |
https://doaj.org/article/07a71ab9289e41afbc2c2c2cd4272325 |
| Accession Number: |
edsdoj.07a71ab9289e41afbc2c2c2cd4272325 |
| Database: |
Directory of Open Access Journals |
