Intestinal barrier function, caecal microbiota and growth performance of thermoneutral or heat stressed broiler chickens fed reduced crude protein diets supplemented with guanidinoacetic acid

Bibliographic Details
Title: Intestinal barrier function, caecal microbiota and growth performance of thermoneutral or heat stressed broiler chickens fed reduced crude protein diets supplemented with guanidinoacetic acid
Authors: Reza Barekatain, Vivienne Inhuber, Nishchal Sharma, Tanya Nowland, Thi Thu Hao Van, Robert J. Moore, David Cadogan
Source: Poultry Science, Vol 104, Iss 2, Pp 104792- (2025)
Publisher Information: Elsevier, 2025.
Publication Year: 2025
Collection: LCC:Animal culture
Subject Terms: Guanidinoacetic acid, Intestinal permeability, Microbiota, Tight junction proteins, Animal culture, SF1-1100
More Details: The effectiveness of guanidinoacetic acid (GAA) in reduced protein (RP) diets on performance and gut health of broilers under heat stress is largely unknown. A 35-d experiment was conducted using four dietary treatments: a standard protein diet (SP, 22.1 and 20.7% CP in grower and finisher), a RP diet (20.1 and 18.7% in grower and finisher), a RP diet with 0.092% GAA per kg diet substituting 50% of supplemented arginine (GAA50) at one-to-one ratio and a RP diet with the same amount of GAA added on top (GAAtop). Day-old male Ross 308 chicks were assigned to 64 pens (10 birds each) in two rooms. In each room, each diet was replicated 8 times. From d 25 to 35, birds in one room were subjected to a cyclic heat stress (32±1 °C for 8 h). There was no interaction between diets and heat stress for any of the studied parameters. GAA50 followed by GAAtop significantly decreased the feed intake during the finisher phase (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 0032-5791
Relation: http://www.sciencedirect.com/science/article/pii/S003257912500029X; https://doaj.org/toc/0032-5791
DOI: 10.1016/j.psj.2025.104792
Access URL: https://doaj.org/article/069c5eeff27f4886bc0aa17fb0c0b699
Accession Number: edsdoj.069c5eeff27f4886bc0aa17fb0c0b699
Database: Directory of Open Access Journals
More Details
ISSN:00325791
DOI:10.1016/j.psj.2025.104792
Published in:Poultry Science
Language:English