Hemoporfin-mediated photodynamic therapy for angiokeratoma corporis diffusum: A case report

Bibliographic Details
Title: Hemoporfin-mediated photodynamic therapy for angiokeratoma corporis diffusum: A case report
Authors: Jing Liu, Meng-yao Yang, Jun Zhou, Youbao Li, Zhao Wang, Weihui Zeng, Songmei Geng
Source: Photodiagnosis and Photodynamic Therapy, Vol 45, Iss , Pp 103828- (2024)
Publisher Information: Elsevier, 2024.
Publication Year: 2024
Collection: LCC:Medicine (General)
Subject Terms: Hemoporfin-PDT, ACD, Angiokeratoma Corporis diffusum, Photodynamic Therapy, Medicine (General), R5-920
More Details: Significance: Angiokeratoma corporis diffusum (ACD) is one type of angiokeratomas which are characterized on histology by superficial dilated capillaries with epidermal proliferation. ACD seriously influences patients’ appearance and quality of life. Many therapies have been used to solved this problem. However, all the treatments have not been proved very effective. Hemoporfin-mediated photodynamic therapy (Hemoporfin-PDT) was considered recently as a promising treatment for PWS according to the principle of targeted photodynamic destruction of the vascular wall of the lesion. Approach: approach: A 27-year-old male patient diagnosed with angiokeratoma corporis diffusum (ACD) by skin tissue biopsy has undergone pulsed dye laser for times, but the result was unsatisfying. After evaluating and obtaining the patient's agreement, we utilized Hemoporfin-PDT with 530 nm LED green light to treat ACD. When followed up in the 1 year after 2 treatments, the patient was pleased with the efficacy that most red papules on his face disappeared. Results: The patient achieved great improvement after two treatments. Conclusions: Hemoporfin-PDT could be used to treat ACD.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1572-1000
Relation: http://www.sciencedirect.com/science/article/pii/S1572100023005550; https://doaj.org/toc/1572-1000
DOI: 10.1016/j.pdpdt.2023.103828
Access URL: https://doaj.org/article/061594dced4142c9881a41d48dc07506
Accession Number: edsdoj.061594dced4142c9881a41d48dc07506
Database: Directory of Open Access Journals
More Details
ISSN:15721000
DOI:10.1016/j.pdpdt.2023.103828
Published in:Photodiagnosis and Photodynamic Therapy
Language:English