Bibliographic Details
| Title: |
Associations between cohort derived dementia and COVID-19 serological diagnosis among older Black adults in rural South Africa |
| Authors: |
Nigel Walsh Harriman, Darina T. Bassil, Meagan T. Farrell, Jacques Du Toit, F. Xavier Gómez-Olivé Casas, Stephen M. Tollman, Lisa F. Berkman |
| Source: |
Frontiers in Public Health, Vol 11 (2024) |
| Publisher Information: |
Frontiers Media S.A., 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Public aspects of medicine |
| Subject Terms: |
COVID-19, older Black adults, South Africa, rural areas, Alzheimer’s disease and related dementias, Public aspects of medicine, RA1-1270 |
| More Details: |
ObjectivesThis study investigates the association between cohort derived dementia and serologically confirmed SARS-CoV-2 infection, an underexplored phenomena in low-and middle-income countries. Examining this relationship in a rural South African community setting offers insights applicable to broader healthcare contexts.MethodsData were collected from Black South Africans in the Mpumalanga province who participated in the Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa. Cohort derived dementia was developed using a predictive model for consensus-based dementia diagnosis. Multinomial logistic regression models estimated the association between predicted dementia probability in 2018 and SARS-CoV-2 infection risk in 2021, controlling for demographics, socioeconomic status, and comorbidities.ResultsFifty-two percent of the tested participants had serologically confirmed SARS-CoV-2 infections. In the fully adjusted model, cohort derived dementia was significantly associated with over twice the risk of serological diagnosis of COVID-19 (RRR = 2.12, p = 0.045).ConclusionComplying with COVID-19 prevention recommendations may be difficult for individuals with impaired cognitive functioning due to their symptoms. Results can inform community-based public health initiatives to reduce COVID-19 transmission among South Africa’s rapidly aging population. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2296-2565 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fpubh.2023.1304572/full; https://doaj.org/toc/2296-2565 |
| DOI: |
10.3389/fpubh.2023.1304572 |
| Access URL: |
https://doaj.org/article/06081b1e7aca4c24bc899e5177dbc459 |
| Accession Number: |
edsdoj.06081b1e7aca4c24bc899e5177dbc459 |
| Database: |
Directory of Open Access Journals |
