Bibliographic Details
| Title: |
Validity of dynamic contrast-enhanced magnetic resonance imaging of the breast versus diffusion-weighted imaging and magnetic resonance spectroscopy in predicting the malignant nature of non-mass enhancement lesions |
| Authors: |
Dalia Bayoumi, Farah Ahmed Shokeir, Rasha Karam, Aya Elboghdady |
| Source: |
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 55, Iss 1, Pp 1-15 (2024) |
| Publisher Information: |
SpringerOpen, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Medical physics. Medical radiology. Nuclear medicine |
| Subject Terms: |
Breast cancer, MRI breast, Time–intensity curve, Non-mass enhancement lesions, DWI, MRS, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| More Details: |
Abstract Background Breast cancer is the commonest cancer affecting women worldwide. So, it is important to accurately detect and classify different breast lesions. Noninvasive methods for tissue characterization have increased interest, particularly for early diagnosis. Non-mass enhancement (NME) breast lesions are described in magnetic resonance imaging (MRI) as the presence of enhancement without space-occupying lesions. Several studies have described that certain characteristics can be used as new indicators of malignancy in breast NME lesions. We aimed to study the role of multiparametric-MRI (Mp-MRI) as diffusion-weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) in assessment of NME lesions and to suggest which one offers the greatest diagnostic accuracy. Methods This retrospective study was conducted from March 2017 to December 2023 on 220 NME breast lesions. All lesions were analyzed to study the features of benign and malignant NME lesions using different MRI techniques including dynamic contrast-enhanced MRI (DCE-MRI), DWI, and MRS. Breast MRI was performed at 1.5 Tesla, findings were correlated with histopathological results of all cases. Results Patients’ mean age was 46.56 years with 220 NME breast lesions (54 were benign and 166 were malignant). Invasive ductal carcinoma with ductal carcinoma in situ was the most malignant type representing 93 cases. We found that segmental distribution, heterogeneous enhancement, type III curve, restricted diffusion, lower apparent diffusion coefficient, and positive choline peak were more with malignancy (P = 0.008, 0.02, 0.004, 0.001, and |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
2090-4762 |
| Relation: |
https://doaj.org/toc/2090-4762 |
| DOI: |
10.1186/s43055-024-01267-2 |
| Access URL: |
https://doaj.org/article/05cf3992e1a94a52a99889cca05bafcf |
| Accession Number: |
edsdoj.05cf3992e1a94a52a99889cca05bafcf |
| Database: |
Directory of Open Access Journals |
