Comparing the effects of pulsed and radiofrequency catheter ablation on quality of life, anxiety, and depression of patients with paroxysmal supraventricular tachycardia: a single-center, randomized, single-blind, standard-controlled trial

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Title: Comparing the effects of pulsed and radiofrequency catheter ablation on quality of life, anxiety, and depression of patients with paroxysmal supraventricular tachycardia: a single-center, randomized, single-blind, standard-controlled trial
Authors: Ying Du, Shanshan Ma, Pan Yue, Ying Xu, Ya Wen, Mingzhu Ji, Lingxiao He, Dengbin Liao
Source: Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Publisher Information: BMC, 2024.
Publication Year: 2024
Collection: LCC:Medicine (General)
Subject Terms: Paroxysmal supraventricular tachycardia, Pulsed field ablation, Radiofrequency catheter ablation, Quality of life, Anxiety, Depression, Medicine (General), R5-920
More Details: Abstract Background Radiofrequency catheter ablation (RFCA) may lead to decreased quality of life (QOL) and increased anxiety and depression in patients with paroxysmal supraventricular tachycardia (PSVT), possibly due to the lack of selectivity of the ablation tissue and the long ablation time. In recent years, pulsed field ablation (PFA) has been used for the first time in China to treat PSVT patients because of its ability to ablate abnormal tissue sites in a precise and transient manner. This study was conducted to compare the effects of PFA and RFCA on QOL and psychological symptoms of PSVT patients. Methods We have designed a single-center, randomized, single-blind, standard-controlled trial. A total of 50 participants who met the eligibility criteria would be randomly allocated into the PFA group or RFCA group in a 1:1 ratio. All participants were assessed using the 36-Item Short-Form Health Survey (SF-36) and the Hospital Anxiety and Depression Scale (HADS) at pre-procedure (T0), post-procedure (T1), and 3 months post-procedure (T2). The SPSS 21.0 software was used to analyze the data through Wilcoxon and Fisher’s exact tests and repeated measures ANOVA. Results Twenty-five in the PFA group and 24 in the RFCA group completed the trial. SF-36: (1) Between-group comparison: At T1, PFA group had significantly higher SF-36 scores on physiological function (PF) and general health (GH) than RFCA group, with a treatment difference of 5.61 points and 18.51 points(P 0.05). (2) Within-group comparison: The HADS scores of the PFA and RFCA groups were statistically significant at T2 compared to T0 and T1 (P
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1745-6215
Relation: https://doaj.org/toc/1745-6215
DOI: 10.1186/s13063-024-07971-8
Access URL: https://doaj.org/article/04e06b434eef43bfb26527d161ea2517
Accession Number: edsdoj.04e06b434eef43bfb26527d161ea2517
Database: Directory of Open Access Journals
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ISSN:17456215
DOI:10.1186/s13063-024-07971-8
Published in:Trials
Language:English