Academic Journal
Chemo-free treatment of adult patients with Ph-positive acute lymphoblastic leukemia: latest updates from the 2023 ASH annual meeting
| Title: | Chemo-free treatment of adult patients with Ph-positive acute lymphoblastic leukemia: latest updates from the 2023 ASH annual meeting |
|---|---|
| Authors: | Ting Shi, Hong-Hu Zhu |
| Source: | Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-4 (2024) |
| Publisher Information: | BMC, 2024. |
| Publication Year: | 2024 |
| Collection: | LCC:Diseases of the blood and blood-forming organs LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: | Ph + ALL, Chemo-free, TKIs, Blinatumomab, Venetoclax, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: | Abstract The chemo-free concept represents a new direction for managing adult patients with Ph-positive acute lymphoblastic leukemia (Ph + ALL). The tyrosine kinase inhibitors (TKIs), blinatumomab and venetoclax serve as the backbone of chemo-free regimens; several prospective studies involving these drugs have demonstrated high remission rates and promising, albeit short, survival outcomes. This review summarizes the latest updates on chemo-free regimens in the treatment of adult patients with Ph + ALL, presented at the 2023 ASH annual meeting. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1756-8722 40940306 |
| Relation: | https://doaj.org/toc/1756-8722 |
| DOI: | 10.1186/s13045-024-01539-4 |
| Access URL: | https://doaj.org/article/04cf46a8728e455db300a40940306dca |
| Accession Number: | edsdoj.04cf46a8728e455db300a40940306dca |
| Database: | Directory of Open Access Journals |
| Full text is not displayed to guests. | Login for full access. |
| ISSN: | 17568722 40940306 |
|---|---|
| DOI: | 10.1186/s13045-024-01539-4 |
| Published in: | Journal of Hematology & Oncology |
| Language: | English |