Bibliographic Details
Title: |
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. |
Authors: |
Luke C Pilling, Janice L Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer |
Source: |
PLoS ONE, Vol 12, Iss 9, p e0185083 (2017) |
Publisher Information: |
Public Library of Science (PLoS), 2017. |
Publication Year: |
2017 |
Collection: |
LCC:Medicine LCC:Science |
Subject Terms: |
Medicine, Science |
More Details: |
Variability in red blood cell volumes (distribution width, RDW) increases with age and is strongly predictive of mortality, incident coronary heart disease and cancer. We investigated inherited genetic variation associated with RDW in 116,666 UK Biobank human volunteers.A large proportion RDW is explained by genetic variants (29%), especially in the older group (60+ year olds, 33.8%, |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
1932-6203 |
Relation: |
http://europepmc.org/articles/PMC5619771?pdf=render; https://doaj.org/toc/1932-6203 |
DOI: |
10.1371/journal.pone.0185083 |
Access URL: |
https://doaj.org/article/04a4afe477254fa0ac97b5879cde81ff |
Accession Number: |
edsdoj.04a4afe477254fa0ac97b5879cde81ff |
Database: |
Directory of Open Access Journals |