Effect of vitamin D3 supplementation on serum 25 (OH)D Levels, hand grip strength, blood sugar levels, and cognitive function in the elderly

Bibliographic Details
Title: Effect of vitamin D3 supplementation on serum 25 (OH)D Levels, hand grip strength, blood sugar levels, and cognitive function in the elderly
Authors: Enny Probosari, Hertanto Wahyu Subagio, Tri Indah Winarni, Heri Nugroho, Nurul Ratna Mutu Manikam
Source: Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition, Vol 13, Iss 1, Pp 79-87 (2024)
Publisher Information: Diponegoro University, 2024.
Publication Year: 2024
Collection: LCC:Nutrition. Foods and food supply
Subject Terms: vitamin d3 supplementation, serum 25(oh)d, hand grip strength, blood sugar level, cognitive function, elderly., Nutrition. Foods and food supply, TX341-641
More Details: ABSTRACT Background: The aging process in the elderly can be caused by a decrease in vitamin D precursors and reduced Vitamin D levels due to impaired absorption of Vitamin D. Vitamin D plays a role in cognitive function, acts as an immunomodulator affecting blood glucose levels, promotes muscle atrophy, and affects the intranuclear VDR concentration and gene expression of VDR. Objectives: To determine the effect of vitamin D3 supplementation on Serum 25(OH)D levels, hand grip strength, blood sugar levels, and cognitive function in the elderly. Materials and Methods: This study used a quasi-experimental pre-posttest control group design with a total of 60 subjects included and divided into two groups. The treatment group received vitamin D3 at a dosage of 1000 IU/day for three months, while the control group was given a placebo. Blood serum levels were used to obtained serum 25(OH)D and blood sugar level. Hand grip strength values were measured by a hand grip dynamometer, and cognitive function was assessed using the Mini-Mental State Examination (MMSE) Questionnaire. The data was analyzed using the Wilcoxon test, and the bivariate analysis was performed using the Mann-Whitney test. Results: Most subjects were between 60 and 92 years old and had a vitamin D deficiency. Significant (P
Document Type: article
File Description: electronic resource
Language: Indonesian
ISSN: 2338-3119
Relation: https://ejournal.undip.ac.id/index.php/jgi/article/view/64767; https://doaj.org/toc/2338-3119
DOI: 10.14710/jgi.13.1.79-87
Access URL: https://doaj.org/article/048f56a949a04b9995012b55d375ddf5
Accession Number: edsdoj.048f56a949a04b9995012b55d375ddf5
Database: Directory of Open Access Journals
More Details
ISSN:23383119
DOI:10.14710/jgi.13.1.79-87
Published in:Jurnal Gizi Indonesia: The Indonesian Journal of Nutrition
Language:Indonesian