New and personalized ventilatory strategies in patients with COVID-19

Bibliographic Details
Title: New and personalized ventilatory strategies in patients with COVID-19
Authors: Lucas Rodrigues de Moraes, Chiara Robba, Denise Battaglini, Paolo Pelosi, Patricia R. M. Rocco, Pedro Leme Silva
Source: Frontiers in Medicine, Vol 10 (2023)
Publisher Information: Frontiers Media S.A., 2023.
Publication Year: 2023
Collection: LCC:Medicine (General)
Subject Terms: COVID-19, noninvasive respiratory support, invasive mechanical ventilation, prone position, recruitment maneuvers, extracorporeal membrane oxygenation, Medicine (General), R5-920
More Details: Coronavirus disease (COVID-19) is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus and may lead to severe respiratory failure and the need for mechanical ventilation (MV). At hospital admission, patients can present with severe hypoxemia and dyspnea requiring increasingly aggressive MV strategies according to the clinical severity: noninvasive respiratory support (NRS), MV, and the use of rescue strategies such as extracorporeal membrane oxygenation (ECMO). Among NRS strategies, new tools have been adopted for critically ill patients, with advantages and disadvantages that need to be further elucidated. Advances in the field of lung imaging have allowed better understanding of the disease, not only the pathophysiology of COVID-19 but also the consequences of ventilatory strategies. In cases of refractory hypoxemia, the use of ECMO has been advocated and knowledge on handling and how to personalize strategies have increased during the pandemic. The aims of the present review are to: (1) discuss the evidence on different devices and strategies under NRS; (2) discuss new and personalized management under MV based on the pathophysiology of COVID-19; and (3) contextualize the use of rescue strategies such as ECMO in critically ill patients with COVID-19.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2296-858X
Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1194773/full; https://doaj.org/toc/2296-858X
DOI: 10.3389/fmed.2023.1194773
Access URL: https://doaj.org/article/04623d7551a14c9b8626eeb2f0c781eb
Accession Number: edsdoj.04623d7551a14c9b8626eeb2f0c781eb
Database: Directory of Open Access Journals
More Details
ISSN:2296858X
DOI:10.3389/fmed.2023.1194773
Published in:Frontiers in Medicine
Language:English