Development and validation of prediction model for fall accidents among chronic kidney disease in the community

Bibliographic Details
Title: Development and validation of prediction model for fall accidents among chronic kidney disease in the community
Authors: Pinli Lin, Guang Lin, Biyu Wan, Jintao Zhong, Mengya Wang, Fang Tang, Lingzhen Wang, Yuling Ye, Lu Peng, Xusheng Liu, Lili Deng
Source: Frontiers in Public Health, Vol 12 (2024)
Publisher Information: Frontiers Media S.A., 2024.
Publication Year: 2024
Collection: LCC:Public aspects of medicine
Subject Terms: falls, chronic kidney disease, CHARLS, predictive model, nomogram, Public aspects of medicine, RA1-1270
More Details: BackgroundThe population with chronic kidney disease (CKD) has significantly heightened risk of fall accidents. The aim of this study was to develop a validated risk prediction model for fall accidents among CKD in the community.MethodsParticipants with CKD from the China Health and Retirement Longitudinal Study (CHARLS) were included. The study cohort underwent a random split into a training set and a validation set at a ratio of 70 to 30%. Logistic regression and LASSO regression analyses were applied to screen variables for optimal predictors in the model. A predictive model was then constructed and visually represented in a nomogram. Subsequently, the predictive performance was assessed through ROC curves, calibration curves, and decision curve analysis.ResultA total of 911 participants were included, and the prevalence of fall accidents was 30.0% (242/911). Fall down experience, BMI, mobility, dominant handgrip, and depression were chosen as predictor factors to formulate the predictive model, visually represented in a nomogram. The AUC value of the predictive model was 0.724 (95% CI 0.679–0.769). Calibration curves and DCA indicated that the model exhibited good predictive performance.ConclusionIn this study, we constructed a predictive model to assess the risk of falls among individuals with CKD in the community, demonstrating good predictive capability.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2296-2565
Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2024.1381754/full; https://doaj.org/toc/2296-2565
DOI: 10.3389/fpubh.2024.1381754
Access URL: https://doaj.org/article/02f0369c316348f5a8ea453e1d1f2e8a
Accession Number: edsdoj.02f0369c316348f5a8ea453e1d1f2e8a
Database: Directory of Open Access Journals
More Details
ISSN:22962565
DOI:10.3389/fpubh.2024.1381754
Published in:Frontiers in Public Health
Language:English