Bibliographic Details
| Title: |
Langerhans Cell Histiocytosis with Good Response to Low-Dose Imatinib: Case Report and Literature Review |
| Authors: |
Mohammed Abdulagayoom, Deena Mudawi, Zsolt Lengyel, Hayan Abo Samra, Awni Alshurafa, Mohamed A. Yassin |
| Source: |
Case Reports in Oncology, Vol 16, Iss 1, Pp 511-518 (2023) |
| Publisher Information: |
Karger Publishers, 2023. |
| Publication Year: |
2023 |
| Collection: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| Subject Terms: |
histiocytic cell neoplasms, dendritic cell neoplasms, histiocytosis, tyrosine kinase inhibitors, positron emission tomography scan, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| More Details: |
Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by infiltration of histiocytes and dendritic cells into body organs. While treatment is better established in pediatrics, there is still no consensus on therapy in the adult population. Imatinib has shown promising results in some case reports and a small clinical trial. We present here a fifty-nine-year-old patient with LCH in the lung, liver, and bone who responded well to an imatinib dose of 100 mg daily. Her symptoms improved within 3 months of treatment, and subsequent positron emission tomography-computed tomography (PET/CT) showed resolution of 18F-fluorodeoxyglucose (FDG)-avid lesions. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
1662-6575 |
| Relation: |
https://beta.karger.com/Article/FullText/531230; https://doaj.org/toc/1662-6575 |
| DOI: |
10.1159/000531230 |
| Access URL: |
https://doaj.org/article/02100bad1edc4d029f330846470ae9da |
| Accession Number: |
edsdoj.02100bad1edc4d029f330846470ae9da |
| Database: |
Directory of Open Access Journals |
