Post-operative determinants of chronic pain after primary knee replacement surgery: Analysis of data on 258,386 patients from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man (NJR)

Bibliographic Details
Title: Post-operative determinants of chronic pain after primary knee replacement surgery: Analysis of data on 258,386 patients from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man (NJR)
Authors: Sara Khalid, Hasan Raza Mohammad, Rachael Gooberman-Hill, Cesar Garriga, Rafael Pinedo-Villanueva, Nigel Arden, Andrew Price, Vikki Wylde, Tim J. Peters, Ashley Blom, Andrew Judge
Source: Osteoarthritis and Cartilage Open, Vol 3, Iss 1, Pp 100139- (2021)
Publisher Information: Elsevier, 2021.
Publication Year: 2021
Collection: LCC:Diseases of the musculoskeletal system
Subject Terms: Knee replacement, Osteoarthritis, Epidemiology, Patient outcomes, Pain, Diseases of the musculoskeletal system, RC925-935
More Details: Objective: To identify post-operative risk factors for the development of chronic pain after knee replacement. Design: Primary knee replacements in persons aged ≥18 years between April 2008 and December 2016 from the National Joint Registry, linked with English Hospital Episode Statistics data, and Patient Reported Outcome Measures. The outcome was chronic pain 6-months after surgery (Oxford Knee pain score). Logistic regression modelling identified risk factors for chronic pain outcome. Results: 258,386 patients; 56.7% women; average age 70.1 years (SD ​± ​8.8 years). 43,702 (16.9%) were identified as having chronic pain 6-months post-surgery. Within 3 months of surgery complications were uncommon: intra-operative complications 1224 (0.5%); ≥1 medical complication 6073 (2.4%)); 32,930 (12.7%) hospital readmissions; 3848 (1.5%) re-operation; 835 (0.3%) revision. Post-surgical risk factors of chronic pain were: mechanical complication of prosthesis odds ratio (OR) 1.56 (95% Confidence Interval 1.35, 1.80); surgical site infection OR 1.13 (0.99, 1.29); readmission OR 1.47 (1.42, 1.52); re-operation OR 1.39 (1.27, 1.51); revision OR 1.92 (1.64, 2.25); length of stay e.g. 6+ vs.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2665-9131
Relation: http://www.sciencedirect.com/science/article/pii/S2665913121000029; https://doaj.org/toc/2665-9131
DOI: 10.1016/j.ocarto.2021.100139
Access URL: https://doaj.org/article/01f30048baa84eaebe3d397feccaf979
Accession Number: edsdoj.01f30048baa84eaebe3d397feccaf979
Database: Directory of Open Access Journals
More Details
ISSN:26659131
DOI:10.1016/j.ocarto.2021.100139
Published in:Osteoarthritis and Cartilage Open
Language:English