Bibliographic Details
Title: |
Transcriptome-wide and stratified genomic structural equation modeling identify neurobiological pathways shared across diverse cognitive traits |
Authors: |
Andrew D. Grotzinger, Javier de la Fuente, Gail Davies, Michel G. Nivard, Elliot M. Tucker-Drob |
Source: |
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022) |
Publisher Information: |
Nature Portfolio, 2022. |
Publication Year: |
2022 |
Collection: |
LCC:Science |
Subject Terms: |
Science |
More Details: |
High genetic overlap across traits requires methods that can be used to disentangle shared and unique biological pathways. Here, the authors introduce TSEM, a multivariate method for examining tissue-specific gene expression, and apply it to identify genes associated with cognitive traits. |
Document Type: |
article |
File Description: |
electronic resource |
Language: |
English |
ISSN: |
2041-1723 |
Relation: |
https://doaj.org/toc/2041-1723 |
DOI: |
10.1038/s41467-022-33724-9 |
Access URL: |
https://doaj.org/article/01eac78397864e54802d15cf51df6c99 |
Accession Number: |
edsdoj.01eac78397864e54802d15cf51df6c99 |
Database: |
Directory of Open Access Journals |