Frequency and Risk Factors of Advanced Neoplasia in Korean Inflammatory Bowel Disease Patients with Low-grade Dysplasia
| Title: | Frequency and Risk Factors of Advanced Neoplasia in Korean Inflammatory Bowel Disease Patients with Low-grade Dysplasia |
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| Authors: | Kyeong Ok Kim, Dong Hyun Kim, Soo-Kyung Park, Division of Gastroenterology, Department of Internal Medicine and Inflammatory Bowel Disease Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Chang Kyun Lee, IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID) |
| Source: | The Korean Journal of Gastroenterology, Vol 85, Iss 1, Pp 34-43 (2025) |
| Publisher Information: | Jin Publishing & Printing Co., 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Medicine |
| Subject Terms: | colorectal neoplasm, inflammatory bowel disease, risk factors, Medicine |
| More Details: | Background/Aims: Studies on the clinical outcomes after detecting low-grade dysplasia (LGD) in patients with inflammatory bowel disease (IBD) are insufficient. This study evaluated the clinical features, frequency, and risk factors for advanced neoplasia in patients with IBD after an LGD diagnosis. Methods: The medical records of 166 patients with IBD from six university hospitals in Korea from 2010 to 2019 were reviewed retrospectively. LGD was diagnosed in all patients during surveillance. The frequency and risk factors for advanced neoplasia were evaluated, and the clinical features of patients with and without advanced neoplasia were compared. Results: Advanced neoplasia developed in 12 patients (six with large LGD, three with tubulovillous adenoma, and three with high-grade dysplasia), and all cases developed from UC. Patients with advanced neoplasia had significantly higher Mayo scores, and colitis-associated dysplasia was more common than sporadic lesions (83.3% vs. 29.9%; p |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English Korean |
| ISSN: | 1598-9992 2233-6869 |
| Relation: | https://www.kjg.or.kr/journal/view.html?uid=6078&vmd=Full; https://doaj.org/toc/1598-9992; https://doaj.org/toc/2233-6869 |
| DOI: | 10.4166/kjg.2024.105 |
| Access URL: | https://doaj.org/article/00c5f7820f2e48dd8ef96f46aa17a6bf |
| Accession Number: | edsdoj.00c5f7820f2e48dd8ef96f46aa17a6bf |
| Database: | Directory of Open Access Journals |
| ISSN: | 15989992 22336869 |
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| DOI: | 10.4166/kjg.2024.105 |
| Published in: | The Korean Journal of Gastroenterology |
| Language: | English Korean |