Iron-Binding Capacity and Antidiabetic Activity of Baby Clam (Corbiculidae sp.) Meat Protein Hydrolysate
| Title: | Iron-Binding Capacity and Antidiabetic Activity of Baby Clam (Corbiculidae sp.) Meat Protein Hydrolysate |
|---|---|
| Authors: | Tam Dinh Le Vo, Thu Huynh, Thuy Thi Le, An Thi Tuong Tran, Bao Chi Vo |
| Source: | Indonesian Journal of Chemistry, Vol 25, Iss 1, Pp 121-132 (2025) |
| Publisher Information: | Department of Chemistry, Universitas Gadjah Mada, 2025. |
| Publication Year: | 2025 |
| Collection: | LCC:Chemistry |
| Subject Terms: | baby clam meat, iron-binding capacity, α-amylase inhibitory activity, protein hydrolysate, Chemistry, QD1-999 |
| More Details: | Baby clam (Corbiculidae sp.) meat is served as a traditional dish in Vietnam, and the antioxidant activity of its protein extract has been discovered. This study evaluates baby clam meat protein hydrolysate's iron-binding capacity (IBC) and antidiabetic activity. Initially, an analysis of the basic chemical composition of the meat was conducted. Subsequently, Alcalase was employed for hydrolysis. The highest IBC and α-amylase inhibition activity were targets for obtaining the best hydrolysis condition, including the clam meat-to-water ratio, enzyme-to-substrate (E:S) ratio, and time. Under the best condition, the hydrolysates demonstrated the IBC of 1246.20 ± 44.00 µg Fe2+/g protein and α-amylase inhibition activity of 48.33 ± 1.44%, approaching three-quarters of the activity of ethylenediaminetetraacetic acid (EDTA) sodium salt and acarbose, respectively. These results served as preliminary data for the development of the protein hydrolysates as a natural iron chelator or α-amylase inhibitor, which could support the treatment of iron deficiency and diabetes. |
| Document Type: | article |
| File Description: | electronic resource |
| Language: | English |
| ISSN: | 1411-9420 2460-1578 |
| Relation: | https://jurnal.ugm.ac.id/ijc/article/view/98947; https://doaj.org/toc/1411-9420; https://doaj.org/toc/2460-1578 |
| DOI: | 10.22146/ijc.98947 |
| Access URL: | https://doaj.org/article/0075cbefbd8e432d916da540316a67fb |
| Accession Number: | edsdoj.0075cbefbd8e432d916da540316a67fb |
| Database: | Directory of Open Access Journals |
| ISSN: | 14119420 24601578 |
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| DOI: | 10.22146/ijc.98947 |
| Published in: | Indonesian Journal of Chemistry |
| Language: | English |