A Case of Concomitant Lung Adenocarcinoma and Pleural Metastasis of Papillary Thyroid Carcinoma With BRAF V600E Mutation

Bibliographic Details
Title: A Case of Concomitant Lung Adenocarcinoma and Pleural Metastasis of Papillary Thyroid Carcinoma With BRAF V600E Mutation
Authors: Akinari Atsumi, Tetsuo Tani, Kota Ishioka, Keisuke Nishikawa, Yasuhide Okamoto, Saeko Takahashi
Source: Respirology Case Reports, Vol 13, Iss 2, Pp n/a-n/a (2025)
Publisher Information: Wiley, 2025.
Publication Year: 2025
Collection: LCC:Diseases of the respiratory system
Subject Terms: BRAF V600E mutation, concomitant cancer, non‐small cell lung carcinoma, papillary thyroid carcinoma, Diseases of the respiratory system, RC705-779
More Details: ABSTRACT A 62‐year‐old woman with a history of papillary thyroid carcinoma presented to our hospital with fever and cough and was diagnosed with stage IV non‐small cell lung carcinoma (NSCLC). One year after chemoimmunotherapy, a re‐biopsy of the left pleural tumour lesion was performed. Histological analysis revealed papillary thyroid carcinoma. Another biopsy was performed on the primary tumour, and the histological analysis of the primary tumour lesion confirmed NSCLC. BRAF V600E mutations were detected in both left pleural metastatic lesions of papillary thyroid carcinoma and the primary tumour of NSCLC. Dabrafenib and trametinib reduced both tumour lesions. Here, we report a rare case of concomitant BRAF V600E‐mutated NSCLC and pleural metastasis from papillary thyroid carcinoma.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2051-3380
Relation: https://doaj.org/toc/2051-3380
DOI: 10.1002/rcr2.70119
Access URL: https://doaj.org/article/006f1f7f4a5f4648a713d73746a56667
Accession Number: edsdoj.006f1f7f4a5f4648a713d73746a56667
Database: Directory of Open Access Journals
More Details
ISSN:20513380
DOI:10.1002/rcr2.70119
Published in:Respirology Case Reports
Language:English