Bibliographic Details
| Title: |
SARS-CoV-2 vaccine-elicited immune responses in solid organ transplant recipients |
| Authors: |
Euri Seo, Eui-Cheol Shin, Min Kyung Jung |
| Source: |
Clinical Transplantation and Research, Vol 38, Iss 4, Pp 247-256 (2024) |
| Publisher Information: |
The Korean Society for Transplantation, 2024. |
| Publication Year: |
2024 |
| Collection: |
LCC:Specialties of internal medicine
LCC:Surgery |
| Subject Terms: |
solid organ transplant recipients, sars-cov-2 vaccine, humoral immune responses, cellular immune responses, Specialties of internal medicine, RC581-951, Surgery, RD1-811 |
| More Details: |
Solid organ transplant recipients (SOTRs) are considered a high-risk group for coronavirus disease 2019 (COVID-19). The adaptive immune responses generated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination include humoral and cellular immune responses. Most studies on the SARS-CoV-2 vaccine have focused primarily on humoral immunity, but cellular immunity is vital for effectively controlling progression to severe COVID-19. In SOTRs, the vaccine-induced adaptive immune response is significantly attenuated compared to the response in healthy individuals. Nevertheless, vaccinated SOTRs exhibit a reduced rate and severity of SARS-CoV-2 infection. This review aims to provide a concise overview of the current understanding of SARS-CoV-2 vaccine-induced immune responses in SOTRs. |
| Document Type: |
article |
| File Description: |
electronic resource |
| Language: |
English |
| ISSN: |
3022-6783 |
| Relation: |
https://www.ctrjournal.org/journal/view.html?doi=10.4285/ctr.24.0062; https://doaj.org/toc/3022-6783 |
| DOI: |
10.4285/ctr.24.0062 |
| Access URL: |
https://doaj.org/article/a002e785ddab477086dd22365f8240d9 |
| Accession Number: |
edsdoj.002e785ddab477086dd22365f8240d9 |
| Database: |
Directory of Open Access Journals |
