microRNAs in Health and Disease
| Title: | microRNAs in Health and Disease |
|---|---|
| Contributors: | Rizzo, Milena, Levantini, Elena |
| Publisher Information: | MDPI - Multidisciplinary Digital Publishing Institute, 2024. |
| Publication Year: | 2024 |
| Subject Terms: | miRNA, mammary gland, lactation, obesogenic diet, microRNA, digital PCR, biomarkers, extraction-free, plasma, obesity, pregnancy, next-generation sequencing, cancer, gene regulation, small nucleolar RNA (snoRNA), small nucleolar derived RNA (sdRNA), microRNA (miRNA), RNA, snoRNA, sdRNA, genetics, ALS mouse model, anti-microRNA-124, intraspinal delivery route, neuroprotection, prevention of glial dysfunction, preservation of motor performance, secretome-based therapy, SOD1-G93A mutation, miR-29, biomarker, therapeutic target, recurrent pregnancy loss, single-nucleotide polymorphism (SNP), extracellular vesicles, biogenesis, cargo sorting, tissue repair and regeneration, uterine leiomyosarcoma, endometrial stromal sarcoma, epigenetics mechanisms, ncRNA, DNA methylation, histones modifications, arrhythmogenic cardiomyopathy, lncRNA, circRNA, pseudogene, ceRNA, Wnt/β-catenin pathway, Hippo pathway, microRNAs1, hippocampus, hypoxia, transposons, LINE1, p53, pediatric cancer, human breast milk, polymerase chain reaction (PCR), microRNA characterization, ovarian cancer, saliva, urine, ascites, blood, biofluids, early diagnosis, screening, intracerebral hemorrhage, aging, RNA medicine, breast cancer, actinic keratosis, cSCC, Medicine: general issues |
| More Details: | This Special Issue delves into the intricate world of miRNAs as modulators of gene expression regulation. These small non-coding RNAs are at the heart of post-transcriptional modulation of gene activity, affecting a myriad of biological processes. The curated selection of articles within this issue offers insights into the roles of miRNAs in health and disease, emphasizing their potential value as therapeutic targets and biomarkers. Featuring original research and in depth-reviews, this Special Issue covers recent miRNA advancements, detailing their regulatory networks and action mechanisms. It highlights new miRNA-linked therapeutic targets and circulating miRNAs as cell-to-cell communication intermediaries. The issue also examines extracellular miRNAs (ex-miRNAs) and their functions, highlighting their presence in biological fluids and their potential utility in clinical diagnostics and disease monitoring. Challenges in miRNA quantification and technological advances for precise measurement are also discussed. The issue traverses the less-charted territories of miRNA research, such as the discovery of small nucleolar-derived miRNAs and the elucidation of transposable elements as unexpected constituents of the miRNA regulatory network. Overall, this collection showcases the evolving nature of miRNA research, offering valuable perspectives for future scientific inquiry and medical innovation. It reflects the drive to decode gene regulation complexities, providing insights for health professionals and researchers at the forefront of gene regulation research. |
| Document Type: | eBook |
| File Description: | application/octet-stream |
| Language: | English |
| ISBN: | 978-3-7258-0843-4 978-3-7258-0844-1 |
| DOI: | 10.3390/books978-3-7258-0844-1 |
| Access URL: | https://directory.doabooks.org/handle/20.500.12854/137917 https://mdpi.com/books/pdfview/book/9181 |
| Rights: | Attribution-NonCommercial-NoDerivatives 4.0 International open access URL: http://purl.org/coar/access_right/c_abf2 URL: https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| Notes: | ONIX_20240514_9783725808434_532 |
| Accession Number: | edsdob.20.500.12854.137917 |
| Database: | Directory of Open Access Books |
| ISBN: | 9783725808434 9783725808441 |
|---|---|
| DOI: | 10.3390/books978-3-7258-0844-1 |
| Language: | English |