Generative 3D Cardiac Shape Modelling for In-Silico Trials

Bibliographic Details
Title: Generative 3D Cardiac Shape Modelling for In-Silico Trials
Authors: Gasparovici, Andrei, Serban, Alex
Publication Year: 2024
Collection: Computer Science
Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Electrical Engineering and Systems Science - Image and Video Processing
More Details: We propose a deep learning method to model and generate synthetic aortic shapes based on representing shapes as the zero-level set of a neural signed distance field, conditioned by a family of trainable embedding vectors with encode the geometric features of each shape. The network is trained on a dataset of aortic root meshes reconstructed from CT images by making the neural field vanish on sampled surface points and enforcing its spatial gradient to have unit norm. Empirical results show that our model can represent aortic shapes with high fidelity. Moreover, by sampling from the learned embedding vectors, we can generate novel shapes that resemble real patient anatomies, which can be used for in-silico trials.
Comment: EFMI Special Topic Conference 2024
Document Type: Working Paper
Access URL: http://arxiv.org/abs/2409.16058
Accession Number: edsarx.2409.16058
Database: arXiv
More Details
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