Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers

Bibliographic Details
Title: Generation of radioisotopes for medical applications using high-repetition, high-intensity lasers
Authors: Batani, Katarzyna Liliana, Rodrigues, Marcia R. D., Bonasera, Aldo, Cipriani, Mattia, Consoli, Fabrizio, Filippi, Francesco, Scisciò, Massimiliano M., Giuffrida, Lorenzo, Kantarelou, Vasiliki, Stancek, Stanislav, Lera, Roberto, Pérez-Hernández, Jose Antonio, Volpe, Luca, Edmond Turcu, I. C., Passoni, Matteo, Vavassori, Davide, Dellasega, David, Maffini, Alessandro, Huault, Marine, Larreur, Howel, Sayo, Louis, Carriere, Thomas, Nicolai, Philippe, Raffestin, Didier, Singappuli, Diluka, Batani, Dimitri
Source: High Power Laser Science and Engineering; January 2025, Vol. 13 Issue: 1
Abstract: AbstractWe used the PW high-repetition laser facility VEGA-3 at Centro de Láseres Pulsados in Salamanca, with the goal of studying the generation of radioisotopes using laser-driven proton beams. Various types of targets have been irradiated, including in particular several targets containing boron to generate α-particles through the hydrogen–boron fusion reaction. We have successfully identified γ-ray lines from several radioisotopes created by irradiation using laser-generated α-particles or protons including 43Sc, 44Sc, 48Sc, 7Be, 11C and 18F. We show that radioisotope generation can be used as a diagnostic tool to evaluate α-particle generation in laser-driven proton–boron fusion experiments. We also show the production of 11C radioisotopes, $\approx 6 \times 10^{6}$ , and of 44Sc radioisotopes, $\approx 5 \times 10^{4}$ per laser shot. This result can open the way to develop laser-driven radiation sources of radioisotopes for medical applications.
Database: Supplemental Index
More Details
ISSN:20954719
20523289
DOI:10.1017/hpl.2024.92
Published in:High Power Laser Science and Engineering
Language:English