Bibliographic Details
| Title: |
I2-DMSO mediated tetra-functionalization of enaminones for the construction of novel furo[2′,3′:4,5]pyrimido[1,2-b]indazole skeletons via in situcapture of ketenimine cations |
| Authors: |
Zhou, You, Wang, Li-Sheng, Lei, Shuang-Gui, Tang, Bo-Cheng, Yu, Zhi-Cheng, Li, Xing, Wu, Yan-Dong, Zheng, Kai-Lu, Wu, An-Xin |
| Source: |
Chinese Chemical Letters; January 2025, Vol. 36 Issue: 1 |
| Abstract: |
The first-ever synthesis of the unknown furo[2′,3′:4,5]pyrimido[1,2-b]indazole skeleton was demonstrated based on the undiscovered tetra-functionalization of enaminones, with simple substrates and reaction conditions. The key to realizing this process lies in the multiple trapping of the in situgenerated ketenimine cation by the 3-aminoindazole, which results in the formation of four new chemical bonds and two new rings in one pot. Moreover, the products of this new reaction were found to exhibit aggregation-induced emission (AIE) without modification. |
| Database: |
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