Bibliographic Details
| Title: |
Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis |
| Authors: |
Gonçalves, Samuel M., Antunes, Daniela, Leite, Luis, Mercier, Toine, Horst, Rob ter, Vieira, Joana, Espada, Eduardo, Pinho Vaz, Carlos, Branca, Rosa, Campilho, Fernando, Freitas, Fátima, Ligeiro, Dário, Marques, António, van de Veerdonk, Frank L., Joosten, Leo A. B., Lagrou, Katrien, Maertens, Johan, Netea, Mihai G., Lacerda, João F., Campos, António, Cunha, Cristina, Carvalho, Agostinho |
| Source: |
mBio; June 2021, Vol. 12 Issue: 3 |
| Abstract: |
The fungal pathogen Aspergillus fumigatuscan cause severe and life-threatening forms of infection in immunocompromised patients. Activation of glycolysis is essential for innate immune cells to mount effective antifungal responses. |
| Database: |
Supplemental Index |
