Bibliographic Details
Title: |
Immune changes in test animals during spaceflight |
Authors: |
Lesnyak, A. T, Sonnenfeld, G., Rykova, M.P., Meshkov, D.O., Mastro, A., Konstantinova, I. |
Source: |
Journal of Leukocyte Biology; September 1993, Vol. 54 Issue: 3 p214-226, 13p |
Abstract: |
Over the past two decades, it has become apparent that changes in immune parameters occur in cosmonauts and astronauts after spaceflight. Therefore, interest has been generated in the use of animal surrogates to better understand the nature and extent of these changes, the mechanism of these changes, and to allow the possible development of countermeasures. Among the changes noted in animals after spaceflight are alterations in lymphocytic blastogenesis, cytokine function, natural killer cell activity, and colonyâstimulating factors. The nature and significance of spaceflightâinduced changes in immune responses will be the focus of this review. |
Database: |
Supplemental Index |