Bibliographic Details
| Title: |
The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis |
| Authors: |
Choi, Jinkuk, Gao, Jie, Kim, Jaekwang, Hong, Cynthia, Kim, Jungsu, Tontonoz, Peter |
| Source: |
Science Translational Medicine; November 2015, Vol. 7 Issue: 314 p314ra184-314ra184, 1p |
| Abstract: |
Inhibiting the E3 ubiquitin ligase Idol in a mouse model of Alzheimer’s-like pathology ameliorates disease severity by promoting clearance of Aβ peptides by microglia. |
| Database: |
Supplemental Index |
