Bibliographic Details
| Title: |
Potential applications of biosurfactants produced by different Pseudomonas syringae: A comparative study on interfacial activity, antimicrobial efficacy, and cytotoxicity. |
| Authors: |
Haidar, Carla N., Taddia, Antonela, Sortino, Maximiliano, López, Debora, Malpiedi, Luciana Pellegrini |
| Source: |
Biocatalysis & Agricultural Biotechnology; Jun2024, Vol. 58, pN.PAG-N.PAG, 1p |
| Subject Terms: |
CYTOTOXINS, BIOSURFACTANTS, RHAMNOLIPIDS, PSEUDOMONAS syringae, VEGETABLE oils, STAPHYLOCOCCUS aureus, SURFACE active agents, COMPARATIVE studies |
| Abstract: |
Finding novel biocompatible compounds with adequate interfacial activity and low toxicity still represents a great challenge for the scientific community. In this context , this work aims to compare for the first time the potential applications of biosurfactants produced by three Pseudomonas syringae pathovars : P. syringae pv tabaci (TA), P. syringae pv tomato (TO) and P. syringae pv syringae (SY). Isolated lipopeptides proved excellent emulsifying activity against a great variety of hydrocarbons and vegetable oils. The lowest minimum inhibitory concentrations against the pathogenic strain Staphylococcus aureus were observed for the biosurfactants produced by TA and SY (0.375 mg/mL). Non-cytotoxic effects were observed for concentrations of up to 10 mg/mL for these BS, and they proved differential cytotoxicity against cancer cell lines. These results open perspectives for the application of these surfactants as low-toxic bioemulsifiers and biotherapeutics. • All Psedomonas syringae pathovars produced a mixture of lipopeptides. • Biosurfactants exhibited notable emulsifying capacity against hydrophobic substrates. • Antibacterial assessments confirm inhibitory effects on Staphylococcus aureus. • Cytotoxicity evaluation shows low-toxicity against normal human cells. [ABSTRACT FROM AUTHOR] |
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| Database: |
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