Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process.

Bibliographic Details
Title: Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process.
Authors: Otte, Douglas A. L., Larson, Reed T., Alwedi, Embarek, Armiger, Travis, Chen, Yonggang, Chung, Cheol K., Corry, James, Desmond, Richard, Fier, Patrick S., Franklin, Robert D., Guetschow, Erik D., Hall, Jackson R., Halsey, Holst M., Hartmanshenn, Clara, Jellett, Lisa, Kuhl, Nadine, Lévesque, François, McMullen, Jonathan P., Patel, Pratiq A., Paulines, Mellie June
Source: Organic Process Research & Development; 5/17/2024, Vol. 28 Issue 5, p1402-1410, 9p
Database: Supplemental Index
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ISSN:10836160
DOI:10.1021/acs.oprd.3c00510
Published in:Organic Process Research & Development
Language:English