Bibliographic Details
| Title: |
Helicobacter pylori infection and the occurrence and severity of gastrointestinal symptoms during pregnancy. |
| Authors: |
Weyermann, Maria, Brenner, Herman, Adler, Guido, Yasar, Zemine, Handke-Vesely, Annette, Grab, Dieter, Kreienberg, Rolf, Rothenbacher, Dietrich, Brenner, Hermann |
| Source: |
American Journal of Obstetrics & Gynecology; Aug2003, Vol. 189 Issue 2, p526-531, 6p, 5 Charts |
| Subject Terms: |
HELICOBACTER pylori infections, GASTROINTESTINAL diseases, PREGNANCY complications |
| Abstract: |
Objective: We investigated the possible role of Helicobacter pylori infection in the occurrence and severity of gastrointestinal symptoms during pregnancy in a large group of mothers after delivery.Study Design: Between November 2000 and November 2001, mothers were recruited after delivery at the Department of Gynecology and Obstetrics at the University of Ulm. Present H pylori infection was determined by (13)C-urea breath test. Associations between gastrointestinal symptoms during pregnancy (sickness, vomiting, increased saliva production, heartburn) and H pylori infection were quantified by crude and adjusted odds ratios with 95% CI.Results: Twenty-three percent of the 898 mothers had a current H pylori infection. Eighty-four percent of the mothers reported at least one of the evaluated gastrointestinal symptoms, and 30% of the mothers reported at least one physician visit because of the severity of these symptoms. None of the analyzed gastrointestinal symptoms showed an association to a current H pylori infection after an adjustment for the covariates, even after a virulence marker of H pylori infection was taken into account.Conclusion: This study does not support an involvement of H pylori infection in the generation of gastrointestinal symptoms during pregnancy. [ABSTRACT FROM AUTHOR] |
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| Database: |
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