Bibliographic Details
Title: |
8-hydroxy-2-(di-n-propylamino)tetralin intervenes with neural cell apoptosis following diffuse axonal injury. |
Authors: |
Zhenli Mao, Zhenquan Song, Gang Li, Wei Lv, Xu Zhao, Bin Li, Xinli Feng, Youli Chen |
Source: |
Neural Regeneration Research; 1/15/2013, Vol. 8 Issue 2, p133-142, 10p |
Subject Terms: |
BRAIN injury treatment, HYPOTHERMIA, NERVOUS system regeneration, APOPTOSIS prevention, BAX protein, LABORATORY rats |
Abstract: |
The article presents a study which discusses the neuroprotective effect of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) for the treatment of traumatic brain injury among rat models. Topics include the reduction of neural cell apoptosis, the caspase-3 and Bax protein expression, and the development of mild hypothermia in rats with diffuse axonal injury. |
Database: |
Complementary Index |