| Title: |
Serum Receptor Activator of Nuclear Factor-κ B Ligand, Osteoprotegrin, and Intact Parathyroid Hormone in Hemodialysis and Renal Transplant Patients. |
| Authors: |
Rashtchizadeh, Nadereh, Ghorbanihaghjo, Amir, Argani, Hassan, Mahmoudi Meimand, Saeed, Safa, Javid, Vatankhahan, Hamidreza, Shahidi, Maryam |
| Source: |
Therapeutic Apheresis & Dialysis; Dec2012, Vol. 16 Issue 6, p600-604, 5p, 1 Chart, 2 Graphs |
| Abstract: |
Serum receptor activator of nuclear factor-κ B ligand and osteoprotegrin are mediated to vascular calcification in the general population. Our knowledge is very sparse in hemodialysis and renal transplant patients. Receptor activator of nuclear factor-κ B ligand, osteoprotegrin, intact parathyroid hormone, calcium, and phosphorus were measured in blood samples of 45 hemodialysis and 45 age-matched renal transplant patients. Osteoprotegrin ( P = 0.001) and intact parathyroid hormone ( P = 0.001) levels in the hemodialysis patients were higher than the renal transplant recipients. Osteoprotegrin had positive correlation with duration of dialysis and age in the hemodialysis (r = 0.88, P = 0.001 and r = 0.34, P = 0.02, respectively) and renal transplant patients (r = 0.92, P = 0.001 and r = 0.46, P = 0.001, respectively). Hemodialysis patients have higher osteoprotegrin levels than the renal transplant recipients. It may act as a protective factor for renal osteodystrophy or only as a secondary phenomenon of advanced renal failure. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
