Bibliographic Details
| Title: |
Platelet-Enriched Fibrin Glue and Platelet-rich Plasma in the Repair of Bone Defects Adjacent to Titanium Dental Implants. |
| Authors: |
Tae-Min You, Byung-Ho Choi, Shi-Jiang Zhu, Jae-Hyung Jung, Seoung-Ho Lee, Jin-Young Huh, Hyun-Jung Lee, Jingxu Li |
| Source: |
International Journal of Oral & Maxillofacial Implants; May/Jun2007, Vol. 22 Issue 3, p417-422, 6p, 4 Color Photographs, 1 Chart |
| Subject Terms: |
FIBRIN tissue adhesive, BLOOD platelets, BLOOD plasma, BONE regeneration, DENTAL implants, BONE grafting |
| Abstract: |
Purpose: The aim of this study was to compare the effects of platelet-enriched fibrin glue and plateletrich plasma (PRP) on the repair of bone defects adjacent to titanium dental implants. Materials and Methods: In 6 mongrel dogs, 3 screw-shaped titanium dental implants per dog were placed into the osteotomy sites in the tibia. Before implantation, a standardized gap (2.0 mm) was created between the implant surface and the surrounding bone walls. Six gaps were left empty (control group), 6 gaps were filled with autogenous particulate bone mixed with PRP (PRP group), and 6 gaps were filled with autogenous particulate bone mixed with platelet-enriched fibrin glue (fibrin glue group). Results: After 6 weeks, the bone-implant contact was 59.7% in the fibrin glue group, 29.2% in the PRP group, and 10.2% in the control defects; this difference was statistically significant (P < .05). Discussion and Con- clusion: Greater bone-implant contact was achieved with platelet-enriched fibrin glue than with PRP. The results indicate that platelet-enriched fibrin glue can induce a stronger peri-implant bone reaction than PRP in the treatment of bone defects adjacent to titanium dental implants. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
