Iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion following periorbital aesthetic Poly‐D, L‐lactic acid filler injections – a case report.

Bibliographic Details
Title: Iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion following periorbital aesthetic Poly‐D, L‐lactic acid filler injections – a case report.
Authors: Chen, I-Hsien, Cheng, Kai-Chun, Chen, Kuo-Jen
Source: Journal of Cosmetic & Laser Therapy; 2025, Vol. 27 Issue 3, p98-101, 4p
Subject Terms: RETINAL artery occlusion, DERMAL fillers, OPHTHALMOLOGIC emergencies, LACTIC acid, VISION disorders, ANATOMY
Abstract: Introduction: Poly‐D, L‐lactic acid (PDLLA), a new dermal filler, has gained popularity in cosmetic surgery due to its biodegradability, safety, and rejuvenating effects. While the literature has primarily focused on dermal reactions as side effects of PDLLA injections, ophthalmic complications are rarely mentioned. Case description: We describe a presentation of severe visual loss and ophthalmalgia in a patient after injection with PDLLA subcutaneous filler at the nasal region who had been diagnosed with right eye iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion. Despite treatment with ocular massage, intravitreal Aflibercept injection, and Hyperbaric Oxygen Therapy, her vision remained persistently impaired. Discussion and conclusion: This appears to be the first reported case of iatrogenic ocular ischemic syndrome combined with central retinal artery occlusion following PDLLA subcutaneous filler treatment. We emphasize the importance of understanding facial arterial anatomy and raise awareness of this rare visual complication associated with PDLLA. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Cosmetic & Laser Therapy is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
More Details
ISSN:14764172
DOI:10.1080/14764172.2025.2478142
Published in:Journal of Cosmetic & Laser Therapy
Language:English