Bibliographic Details
| Title: |
Sinonasal, Nasopharyngeal, Upper Oral, and Oropharyngeal Cavity Adenoid Cystic Carcinoma: An International Multicenter Retrospective Study on 457 Patients. |
| Authors: |
Schiavo, Gloria, Zanoni, Mario Turri, Mattavelli, Davide, Vinciguerra, Alessandro, Conti, Carlo, Gravante, Giacomo, Orlandi, Ester, Vischioni, Barbara, Verillaud, Benjamin, Guo, Yunxia Sarah, Lechner, Matt, Lund, Valerie, Creber, Nathan, Borsetto, Daniele, Herman, Philippe, Hanna, Ehab Y., Castelnuovo, Paolo Gm, Nicolai, Piero, Ferrari, Marco |
| Source: |
Journal of Neurological Surgery. Part B. Skull Base; 2025 Supplement 1, Vol. 86, pS1-S576, 576p |
| Subject Terms: |
SYMPTOM burden, ADENOID cystic carcinoma, OVERALL survival, MULTIVARIATE analysis, UNIVARIATE analysis, PROGRESSION-free survival, SURVIVAL analysis (Biometry) |
| Abstract: |
This article presents a retrospective study on 457 patients with adenoid cystic carcinoma (ACC) in the sinonasal tract, nasopharynx, and upper oral and oropharyngeal cavity. The study aims to define optimal treatment strategies for ACC and identify a new definition of recovery due to its unique behavior. Findings indicate that gross total resection without adjuvant radiotherapy leads to higher disease-specific survival, while patients with noncurative treatment intent have a worse prognosis. The study also highlights the significant burden of symptoms and toxicity from retreatments, as well as the potential for local and distant metastases years after primary treatment. [Extracted from the article] |
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| Database: |
Complementary Index |
