Association of body round index with chronic kidney disease: a population-based cross-sectional study from NHANES 1999–2018.

Bibliographic Details
Title: Association of body round index with chronic kidney disease: a population-based cross-sectional study from NHANES 1999–2018.
Authors: Cao, Hongliang, Shi, Chengdong, Aihemaiti, Zulipikaer, Dai, Xianyu, Yu, Fangqiu, Wang, Song
Source: International Urology & Nephrology; Mar2025, Vol. 57 Issue 3, p965-971, 7p
Abstract: Background: Complex nexuses between obesity and chronic kidney disease (CKD) have been reported. Nevertheless, the link between the body roundness index (BRI), an indicator utilized to measure body fat distribution, and CKD risk has been unexplored. Methods: We utilized publicly available data from ten survey cycles (1999–2018) of the National Health and Nutrition Examination Survey (NHANES) in the United States. We examined the association between BRI and CKD risk using multivariable logistic regression, subgroup analysis, interaction tests, and smooth curve fitting. Results: The study ultimately involved 41,953 participants, 3,123 (7.44%) of whom had CKD. Multivariable logistic regression, adjusted for covariates, identified high BRI levels in quartile 4 as a risk factor for CKD (OR = 1.30, 95% CI 1.12–1.50, P = 0.0005). This association remained consistent across subgroups (P for interaction > 0.05). Smoothed curve fitting exhibited a roughly linear positive correlation between BRI and CKD. Conclusion: According to our study, BRI was related to CKD in a roughly linear way, suggesting a novel indicator for improving prevention and treatment for the CKD population. Nevertheless, additional research is needed to identify the association. [ABSTRACT FROM AUTHOR]
Copyright of International Urology & Nephrology is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
More Details
ISSN:03011623
DOI:10.1007/s11255-024-04275-3
Published in:International Urology & Nephrology
Language:English