Bibliographic Details
| Title: |
Association between Severity of Nonalcoholic Fatty Liver and Left Ventricular Diastolic Dysfunction Assessed by Tissue Doppler Echocardiography. |
| Authors: |
Abdel Rashid, Mahmoud Abdel Aziz, El Sebaie, Maha Hamed, Nasr Fouda, Mohamed Reda, Salem, Ahmed Mohamed |
| Source: |
Zagazig University Medical Journal; Jan2025, Vol. 31 Issue 1, p28-34, 7p |
| Subject Terms: |
FATTY liver, NON-alcoholic fatty liver disease, DOPPLER echocardiography, ASYMPTOMATIC patients, VENTRICULAR dysfunction |
| Abstract (English): |
Background: Numerous metabolic risk factors are shared by a wide range of cardiac problems that may be linked to nonalcoholic fatty liver disease (NAFLD). The purpose of this study was to determine if tissue Doppler echocardiography-measured left ventricular (LV) diastolic dysfunction and nonalcoholic fatty liver disease are related. Methods: In this prospective cross-sectional investigation, 92 NAFLD patients were involved and were divided according to Transabdominal ultrasound into three groups: Group I (grade I fatty liver) included 27 patients, Group II (grade II fatty liver) included 29 patients and group III (grade III fatty liver) included 36 patients. All patients underwent transabdominal ultrasound and measuring tissue Doppler transthoracic echocardiography e septal velocity, E/e, E/A ratio, peak E-wave velocity, and peak A-wave velocity. Results: Regarding echocardiographic functions, there was a statistical significant difference in the NAFLD degrees between the three groups; group III had higher E/A, E/e' ratio, and LA. While A and e' levels were higher among group I when compared with the other groups. E/e' ratio was positively associated with NAFLD grades, while positively associated with HTN. HTN, NAFLD, TC and LA can be used as independent factors for predicting diastolic dysfunction among the studied groups. Conclusions: In asymptomatic patient there was a significant association between NAFLD and cardiac diastolic dysfunction as NAFLD grades were associated with E/e' ratio (diastolic dysfunction). [ABSTRACT FROM AUTHOR] |
| Abstract (Arabic): |
المقال يركز على العلاقة بين شدة مرض الكبد الدهني غير الكحولي (NAFLD) واضطراب الانبساط البطيني الأيسر، الذي تم تقييمه من خلال تخطيط صدى القلب باستخدام دوبلر النسجي. شملت دراسة 92 مريضًا مصابين بـ NAFLD، وتم تصنيفهم إلى ثلاث مجموعات بناءً على شدة حالتهم، مما كشف عن اختلافات كبيرة في المعايير الإيكو القلبية بين المجموعات. تشير النتائج إلى أن درجات أعلى من NAFLD مرتبطة بزيادة اضطراب الانبساط، كما تم قياسه من خلال نسبة E/e'، وتقترح أن ارتفاع ضغط الدم، وشدة NAFLD، ومستوى الكوليسترول الكلي، وحجم الأذين الأيسر يمكن أن تكون مؤشرات مستقلة لاضطراب الانبساط. وتخلص الدراسة إلى وجود ارتباط ملحوظ بين NAFLD واضطراب الانبساط القلبي لدى المرضى الذين لا تظهر عليهم أعراض. [Extracted from the article] |
|
Copyright of Zagazig University Medical Journal is the property of Association of Arab Universities and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Complementary Index |
