Treatment of Renal Artery Aneurysm by ex situ Repair and Autotransplantation: A Nationwide Cohort Study.

Bibliographic Details
Title: Treatment of Renal Artery Aneurysm by ex situ Repair and Autotransplantation: A Nationwide Cohort Study.
Authors: Fang, Yitian, Kimenai, Hendrikus J.A.N., de Bruin, Ron W.F., de Vries, Dorottya K., Petri, Bart-Jeroen, Warlé, Michiel C., Tielliu, Ignace F.J., van Laanen, Jorinde, Idu, Mirza M., Pol, Robert A., Minnee, Robert C.
Source: European Surgical Research; 2024, Vol. 65 Issue 1, p123-129, 7p
Subject Terms: RENAL artery diseases, RENAL artery, SURGICAL complications, OPERATIVE surgery, GLOMERULAR filtration rate
Abstract: Introduction: Renal artery aneurysm (RAA) is a rare vascular disease with a mortality rate of up to 80% upon rupture. This study aimed to investigate the safety and efficacy of ex situ repair and autotransplantation for endovascularly untreatable RAA. Methods: A retrospective nationwide cohort study was conducted in RAA patients undergoing ex situ repair and autotransplantation in the Netherlands. Surgical techniques, postoperative complications, and graft outcomes were assessed. Results: Ex situ repair was performed in 9 patients with 11 RAAs. Eight RAAs were located at the first bifurcation, one on the main trunk, one on the first branch, and one on the second branch. Nephrectomy was performed via laparoscopy (n = 7), robotic-assisted laparoscopy (n = 1), and laparotomy (n = 1). Postoperative complications were recorded in 4 patients, including bowel obstruction, delirium, pneumonia, and hydronephrosis due to double-J dislocation. The median estimated glomerular filtration rate was 83 mL/min/1.73 m2 pretransplant and 88 mL/min/1.73 m2 posttransplant. By an average follow-up of 32 months, 2 patients had died due to lung adenocarcinoma and stroke, while all autotransplanted kidneys had good patency and remained functional. Conclusions: Ex situ repair and autotransplantation are safe and feasible for endovascularly untreatable RAA cases. Larger cohorts with longer follow-up periods are necessary to further evaluate the role of this surgical approach. [ABSTRACT FROM AUTHOR]
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Database: Complementary Index
More Details
ISSN:0014312X
DOI:10.1159/000541814
Published in:European Surgical Research
Language:English