Bibliographic Details
Title: |
Editorial: Developing next-generation therapeutics to defeat mutation-driven cancer. |
Authors: |
Chow, Frances, Lamoureux, François, Moriceau, Gatien |
Source: |
Frontiers in Immunology; 2024, p1-2, 2p |
Subject Terms: |
T-cell exhaustion, THERAPEUTICS, NON-small-cell lung carcinoma, AP-1 transcription factor, COMBINATION drug therapy |
Abstract: |
The editorial in Frontiers in Immunology discusses the challenges posed by mutation-driven cancers and the need for innovative therapeutic strategies to combat them. The research topic focuses on preclinical studies, target-based mechanisms for combination therapies, and approaches to overcome resistance to current treatments. The editorial highlights a study on predicting pancreatic cancer prognosis based on KRAS mutation status, as well as reviews on the potential of antibody-drug conjugates for lung cancer and FGFR-targeting therapies for urothelial carcinoma. The authors emphasize the importance of ongoing research in developing next-generation therapeutics to address mutation-driven cancers. [Extracted from the article] |
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Database: |
Complementary Index |