Engagement in Care, Awareness, and Interest in Long-Acting Injectable Anti-Retroviral Therapy.

Bibliographic Details
Title: Engagement in Care, Awareness, and Interest in Long-Acting Injectable Anti-Retroviral Therapy.
Authors: Stout, Jacob A., Allamong, Maxwell, Hung, Frances, Link, Katherine, Chan, Cliburn, Muiruri, Charles, Sauceda, John, McKellar, Mehri S.
Source: AIDS & Behavior; Oct2024, Vol. 28 Issue 10, p3315-3325, 11p
Subject Terms: INTELLECT, CONTROLLED release preparations, RESEARCH funding, HUMAN beings, DESCRIPTIVE statistics, HIGHLY active antiretroviral therapy, SURVEYS, ODDS ratio, CONFIDENCE intervals
Geographic Terms: UNITED States
Abstract: Long Acting Injectable (LAI) therapy to treat HIV is an alternative to daily oral medications. The success of early roll-out of LAI to eligible patients requires a better understanding of patients' awareness and interest in this novel therapy. We administered an electronic survey to patients attending an urban HIV clinic in the US South. Eligible participants were 18 + years old with a most recent HIV-1 viral load < 200 copies/ml, without any evidence of genotypic resistance to LAI components or chronic hepatitis B. Survey recipients were asked about current treatment, engagement in care, and knowledge of LAI. Between January-April 2023, 480 patients were screened; 319 were eligible, and 155 (49%) completed the survey. The majority (119, 77%) were aware of, and 87 (56%) were interested in LAI. In regression analysis, only age was associated with interest in LAI (OR 0.95, 95% CI 0.92,0.99). Among proposed benefits of injectables, ease of travel without pills, lack of daily pill-taking, and fewer medication interactions were most appealing. Among proposed concerns with injectables, higher cost and insurance coverage of the new medicine were most worrisome. A large majority of people with HIV (PWH) are aware of the newest treatment available, and just over half of our sample expressed interest in LAI. Older age was associated with lower interest in LAI. LAI is appealing for its convenience, privacy, and avoidance of drug interactions, while the increased costs associated with LAI need to be addressed. [ABSTRACT FROM AUTHOR]
Copyright of AIDS & Behavior is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Complementary Index
More Details
ISSN:10907165
DOI:10.1007/s10461-024-04423-x
Published in:AIDS & Behavior
Language:English