Bibliographic Details
| Title: |
A STUDY OF CLINICO -EPIDEMIOLOGICAL AND CORONARY ANGIOGRAPHICAL PROFILE OF PRE MENOPAUSAL WOMEN WITH ACUTE CORONARY SYNDROME IN A TERTIARY CARE HOSPITAL. |
| Authors: |
Ghosh, Niladri, Adhikari, Lipika, Bar, Mita, Kumari, Nikita, Dash, Purnendu |
| Source: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 7, p475-493, 17p |
| Subject Terms: |
ACUTE coronary syndrome, CORONARY artery stenosis, MYOCARDIAL infarction, CORONARY artery disease, CORONARY angiography |
| Abstract: |
Background: Even though Coronary artery disease is one of the leading cause of death globally for both male and female, there is limited data on acute coronary syndrome among pre-menopausal women .The management of acute coronary syndrome is based on rapid diagnosis in order to provide treatment. Female gender is strongly correlated with delayed hospital arrival due to due to low awareness, sociocultural and financial reasons. Risk factors, pathophysiology, presentation may vary in female compared to male. For many years, women have been underdiagnosed and undertreated. Objective: In our study objective was to assess the additional risk factors in pre-menopausal women for Acute Coronary Syndrome and to evaluate the biochemical, electrocardiogram, echocardiography profile and coronary angiographic profile. Methods: This was cross-sectional observational study conducted in Cardiology department of a tertiary care Hospital, West Bengal over a period of 1 yr. The study was conducted over 100 pre-menopausal women patients admitted with Acute Coronary Syndrome in cardiology ward and intensive coronary care unit after fulfilling inclusion and exclusion criteria. All study patients underwent complete physical, biochemical and relevant investigation including Electrocardiogram, Echocardiogram followed by coronary angiography. All data were collected and analysed statistically. Results: This study had shown that young women presenting with ACS (Acute Coronary Syndrome) had significant comorbidities. The mean (±SD) age of the study population was 41.10 (±5.002) years. On echocardiography 49% of study patients had Anterior wall MI (Myocardial infarction), 29% had inferior wall MI, 7% of subjects had global hypokinesia & 10% had no RWMA (Regional wall motion abnormality). In our study the proportions of subjects with significant LMCA(Left Main Coronary Artery) stenosis, LAD(left anterior descending artery) stenosis, LCX(left circumflex artery) stenosis and RCA(Right coronary artery) stenosis on coronary angiography were 11%, 61%, 28% and 34% respectively. Background variables e.g., age, BMI (body mass index), hypertension, diabetes, dyslipidemia, Family history of AMI (Acute myocardial infarction), NYHA class at presentation and ANA profile of the study subjects were not significantly associated with LMCA stenosis. Conclusion: AMI incidence is in rising in young female in India. The present descriptive observational study was conducted over one year duration among randomly selected100 premenopausal women with Acute Coronary Syndrome. Anterior Wall MI was the most common presentation in our study. Obesity, hypertension, diabetes, dyslipidemia were important risk factors & 5% of the subjects had positive ANA profile in this study. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
