| Title: |
Donor-Derived Bartonella quintana Infection in Solid Organ Transplantation: An Emerging Public Health Issue With Diagnostic Challenges. |
| Authors: |
Boodman, Carl, Garcia, Oscar Fernandez, Kabbani, Dima, Villalobos, Armelle Perez Cortes, Beeson, Amy, Marx, Grace E, Griensven, Johan van, Doucette, Karen |
| Source: |
Open Forum Infectious Diseases; Aug2024, Vol. 11 Issue 8, p1-6, 6p |
| Subject Terms: |
CLINICAL pathology, TRANSPLANTATION of organs, tissues, etc., PUBLIC health, BARTONELLA, BACTEREMIA |
| Abstract: |
Bartonella quintana is a louse-borne intracellular bacterium that remains a neglected cause of bacteremia, bacillary angiomatosis, and infective endocarditis among individuals experiencing poverty. In October 2023, Health Canada notified Canadian organ transplantation programs of an outbreak of donor-derived B quintana infection. From March to August 2023, 5 cases of donor-derived B quintana disease were acquired in Alberta, Canada, from 3 deceased donors who had experienced homelessness. Similar cases recently occurred in the United States. In this article, we discuss strategies to screen organ donors and monitor transplant recipients for B quintana infection using epidemiologic risk factors, physical examination signs, and laboratory diagnostic tests. We review the limitations of existing diagnostic tests for B quintana and describe how these problems may be magnified in the organ transplantation context. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
