Bibliographic Details
| Title: |
Comparison between total weight loss and other metrics after bariatric surgery using a multilevel mixed-effects linear regression model. |
| Authors: |
Thobie, Alexandre, Menahem, Benjamin, Pouchucq, Camille, Bouvier, Véronique, Alves, Arnaud, Dejardin, Olivier |
| Source: |
Surgical Endoscopy & Other Interventional Techniques; Jul2024, Vol. 38 Issue 7, p3684-3690, 7p |
| Subject Terms: |
BARIATRIC surgery, WEIGHT loss, GASTRECTOMY, REPEATED measures design, BODY mass index, LAPAROSCOPIC surgery, SURGICAL anastomosis, MULTIPLE regression analysis, TREATMENT effectiveness, TERTIARY care, DESCRIPTIVE statistics, LONGITUDINAL method, CONFIDENCE intervals, GASTRIC bypass, SMALL intestine, OBESITY, EVALUATION |
| Geographic Terms: |
FRANCE |
| Abstract: |
Background: Several tools are used to assess postoperative weight loss after bariatric surgery, including the percentage of excess body weight loss (%EWL), percentage of total weight loss (%TWL), and percentage of excess body mass index (BMI) loss (%EBMIL). A repeated series of measurements should be considered to assess weight loss as accurately as possible. This study aimed to test weight loss metrics. Methods: Data were obtained from a prospective database of patients with obesity who underwent laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) between 2016 and 2017 in a French tertiary referral bariatric center. A multilevel mixed-effects linear regression model with repeated measures was used to analyze repeated weight measurements over time. Results: A total of 435 patients underwent LRYGB (n = 266) or LSG (n = 169). At 2 years, the average %EWL, %EBMIL, and %TWL were 56.8%, 61.3%, and 26.6%, respectively. Patients who underwent LSG experienced lower weight loss (β: − 4233 in %TWL model, β: − 6437 in %EWL model, and β: − 6989 in %EBMIL model) than those who underwent LRYGB. In multivariate mixed analysis, preoperative BMI was not significantly associated with %TWL at 2 years (β, − 0.09 [− 0.22–0.03] p = 0.1). Preoperative BMI was negatively associated with both %EWL (β, − 1.61 [− 1.84–− 1.38] p < 0.0001) and %EBMIL (β, − 1.91 [− 2.16–− 1.66] p < 0.0001). Conclusion: This is the first study to assess %TWL use for postoperative weight measurement, using a multilevel mixed-effects linear regression model %TWL is the measure of choice to assess weight loss following bariatric surgery. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
