| Title: |
EFFECT OF SEVERITY OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON THE RIGHT VENTRICULAR SYSTOLIC FUNCTION. |
| Alternate Title: |
UTICAJ TEŽINE HRONIČNE OPSTRUKTIVNE BOLESTI PLUĆA NA SISTOLNU FUNKCIJU DESNE KOMORE. (Bosnian) |
| Authors: |
Marinković, Marija, Jovanović, Hristina, Nikolić, Nemanja, Nikolić, Tamara, Topalović, Marija, Božanić, Borislav, Perić, Velimir, Petković, Nikola, Jocić, Jasmina, Ćosić, Milica, Kostić, Tomislav, Pejčić, Tatjana |
| Source: |
Acta Medica Medianae; Mar2024, Vol. 63 Issue 1, p64-72, 9p |
| Subject Terms: |
CHRONIC obstructive pulmonary disease, RIGHT ventricular hypertrophy, OBSTRUCTIVE lung diseases, INTERSTITIAL lung diseases, CARDIAC hypertrophy, TRICUSPID valve insufficiency |
| Company/Entity: |
WORLD Health Organization |
| Abstract (English): |
According to the World Health Organization, the most common complication of chronic obstructive pulmonary disease (COPD) is chronic pulmonary heart disease (cor pulmonale chronicum). It represents myocardial hypertrophy of the right ventricle, dilatation and insufficiency of the right ventricle occurring as a result of changes in lung function/structure in the absence of left heart disease. The gold standard in detecting changes in right heart function in patients with COPD is an echocardiographic examination. The primary goal of this research was to determine the influence of the severity of COPD on the values of the right ventricular systolic function parameter, and the secondary goal of this research was to determine the frequency of tricuspid regurgitation in relation to the degree of COPD. For a detailed assessment of the systolic function of the right ventricle, which is important for the objectives of the study, the following parameters were performed: The fractional area change (FAC) of the right ventricle and tricuspid annular plane systolic excursion (TAPSE) in 44 patients with COPD which were divided into four groups according to the global initiative for obstructive lung disease (GOLD) criteria. There was no statistically significant difference between the groups for anthropometric indicators and FEV1 values (%) (p > 0.05).The Kruskal−Wallis test shows that the TAPSE index and FAC values are significantly higher in patients with severe and very severe COPD (p < 0.05). The results of our research show that echocardiographic parameters of the right ventricle such as TAPSE and FAC are very important for assessing its systolic function and that these values decrease proportionally with the progression of the COPD disease. [ABSTRACT FROM AUTHOR] |
| Abstract (Bosnian): |
Prema navodima Svetske zdravstvene organizacije, najčešća komplikacija hronične opstruktivne bolesti pluća (HOBP) jeste hronično plućno srce (cor pulmonale chronicum); ono podrazumeva hipertrofiju miokarda desne komore, dilataciju i insuficijenciju desne komore, koja nastaje kao posledica promena funkcije/strukture pluća, u odsustvu bolesti leve strane srca. Ehokardiografski pregled je zlatni standard u otkrivanju promena funkcije desne strane srca kod obolelih od HOBP-a. Glavni cilj ovog istraživanja bio je da se utvrdi uticaj stepena težine HOBP-a na vrednosti parametara sistolne funkcije desne komore. Sporedni cilj istraživanja bio je da se odredi učestalost trikuspidne regrugitacije u odnosu na stepen HOBP-a. Radi detaljne procene sistolne funkcije desne komore, značajne za ciljeve ove studije, ispitani su sledeći parametri: procentualna frakcija promene površine desne komore (engl. fractional area change – FAC), trikuspidna regurgitacija (TR), amplituda sistolne pokretljivosti trikuspidnog prstena (engl. tricuspid annular plane systolic excursion – TAPSE) (mm). U ispitivanju su učestvovala 44 bolesnika sa HOBP-om, podeljena u četiri grupe prema GOLD (engl. global initiative for obstructive lung disease) kriterijumima. Nije bilo statistički značajne razlike među grupama u pogledu antropometrijskih pokazatelja i vrednosti FEV1(%) (p > 0,05). Na osnovu Kruskal‒Wallisovog testa uočeno je da su vrednosti TAPSE indeksa i FAC-a bile značajno veće kod osoba sa teškim i veoma teškim HOBP-om (p < 0,05). Prilikom poređenja učestalosti TR-a u blagom HOBP-u sa onom u umerenom i u teškom HOBP-u, zapažena je statistički značajna razlika; kada je reč o ovom parametru, statistički značajna razlika postojala je i između umerenog i teškog HOBP-a (p < 0,05). Rezultati našeg istraživanja pokazali su da su ehokardiografski parametri desne komore, kakvi su TAPSE, FAC i TR, veoma važni za procenu njene sistolne funkcije, kao i da je opadanje ovih vrednosti srazmerno sa progresijom HOBP-a. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
