Bibliographic Details
| Title: |
Marine Compounds and Age-Related Diseases: The Path from Pre-Clinical Research to Approved Drugs for the Treatment of Cardiovascular Diseases and Diabetes. |
| Authors: |
Giuliani, Maria Elisa, Bigossi, Giorgia, Lai, Giovanni, Marcozzi, Serena, Brunetti, Dario, Malavolta, Marco |
| Source: |
Marine Drugs; May2024, Vol. 22 Issue 5, p210, 22p |
| Abstract: |
Ageing represents a main risk factor for several pathologies. Among them, cardiovascular diseases (CVD) and type 2 diabetes mellitus (T2DM) are predominant in the elderly population and often require prolonged use of multiple drugs due to their chronic nature and the high proportion of co-morbidities. Hence, research is constantly looking for novel, effective molecules to treat CVD and T2DM with minimal side effects. Marine active compounds, holding a great diversity of chemical structures and biological properties, represent interesting therapeutic candidates to treat these age-related diseases. This review summarizes the current state of research on marine compounds for the treatment of CVD and T2DM, from pre-clinical studies to clinical investigations and approved drugs, highlighting the potential of marine compounds in the development of new therapies, together with the limitations in translating pre-clinical results into human application. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
