Pressure-adjusted venting eliminates start-up delays and compensates for vertical position of syringe infusion pumps used for microinfusion.
| Title: | Pressure-adjusted venting eliminates start-up delays and compensates for vertical position of syringe infusion pumps used for microinfusion. |
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| Authors: | Weiss, Markus, Wendel-Garcia, Pedro David, Cannizzaro, Vincenzo, Grass, Beate, Buehler, Philipp Karl, Kleine-Brueggeney, Maren |
| Source: | Journal of Clinical Monitoring & Computing; Apr2024, Vol. 38 Issue 2, p531-538, 8p |
| Abstract: | Microinfusions are commonly used for the administration of catecholamines, but start-up delays pose a problem for reliable and timely drug delivery. Recent findings show that venting of the syringe infusion pump with draining of fluid to ambient pressure before directing the flow towards the central venous catheter does not counteract start-up delays. With the aim to reduce start-up delays, this study compared fluid delivery during start-up of syringe infusion pumps without venting, with ambient pressure venting, and with central venous pressure (CVP)-adjusted venting. Start-up fluid delivery from syringe pumps using a microinfusion of 1 mL/h was assessed by means of liquid flow measurement at 10, 60, 180 and 360 s after opening the stopcock and starting the pump. Assessments were performed using no venting, ambient pressure venting or CVP-adjusted venting, with the pump placed either at zero, − 43 cm or + 43 cm level and exposed to a simulated CVP of 10 mmHg. Measured fluid delivery was closest to the calculated fluid delivery for CVP-adjusted venting (87% to 100% at the different timepoints). The largest deviations were found for ambient pressure venting (− 1151% to + 82%). At 360 s after start-up 72% to 92% of expected fluid volumes were delivered without venting, 46% to 82% with ambient pressure venting and 96% to 99% with CVP-adjusted venting. CVP-adjusted venting demonstrated consistent results across vertical pump placements (p = 0.485), whereas the other methods had significant variances (p < 0.001 for both). In conclusion, CVP-adjusted venting effectively eliminates imprecise drug delivery and start-up delays when using microinfusions. [ABSTRACT FROM AUTHOR] |
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| Database: | Complementary Index |
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| Items | – Name: Title Label: Title Group: Ti Data: Pressure-adjusted venting eliminates start-up delays and compensates for vertical position of syringe infusion pumps used for microinfusion. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Weiss%2C+Markus%22">Weiss, Markus</searchLink><br /><searchLink fieldCode="AR" term="%22Wendel-Garcia%2C+Pedro+David%22">Wendel-Garcia, Pedro David</searchLink><br /><searchLink fieldCode="AR" term="%22Cannizzaro%2C+Vincenzo%22">Cannizzaro, Vincenzo</searchLink><br /><searchLink fieldCode="AR" term="%22Grass%2C+Beate%22">Grass, Beate</searchLink><br /><searchLink fieldCode="AR" term="%22Buehler%2C+Philipp+Karl%22">Buehler, Philipp Karl</searchLink><br /><searchLink fieldCode="AR" term="%22Kleine-Brueggeney%2C+Maren%22">Kleine-Brueggeney, Maren</searchLink> – Name: TitleSource Label: Source Group: Src Data: Journal of Clinical Monitoring & Computing; Apr2024, Vol. 38 Issue 2, p531-538, 8p – Name: Abstract Label: Abstract Group: Ab Data: Microinfusions are commonly used for the administration of catecholamines, but start-up delays pose a problem for reliable and timely drug delivery. Recent findings show that venting of the syringe infusion pump with draining of fluid to ambient pressure before directing the flow towards the central venous catheter does not counteract start-up delays. With the aim to reduce start-up delays, this study compared fluid delivery during start-up of syringe infusion pumps without venting, with ambient pressure venting, and with central venous pressure (CVP)-adjusted venting. Start-up fluid delivery from syringe pumps using a microinfusion of 1 mL/h was assessed by means of liquid flow measurement at 10, 60, 180 and 360 s after opening the stopcock and starting the pump. Assessments were performed using no venting, ambient pressure venting or CVP-adjusted venting, with the pump placed either at zero, − 43 cm or + 43 cm level and exposed to a simulated CVP of 10 mmHg. Measured fluid delivery was closest to the calculated fluid delivery for CVP-adjusted venting (87% to 100% at the different timepoints). The largest deviations were found for ambient pressure venting (− 1151% to + 82%). At 360 s after start-up 72% to 92% of expected fluid volumes were delivered without venting, 46% to 82% with ambient pressure venting and 96% to 99% with CVP-adjusted venting. CVP-adjusted venting demonstrated consistent results across vertical pump placements (p = 0.485), whereas the other methods had significant variances (p < 0.001 for both). In conclusion, CVP-adjusted venting effectively eliminates imprecise drug delivery and start-up delays when using microinfusions. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Group: Ab Data: <i>Copyright of Journal of Clinical Monitoring & Computing is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10877-023-01101-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 531 Titles: – TitleFull: Pressure-adjusted venting eliminates start-up delays and compensates for vertical position of syringe infusion pumps used for microinfusion. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Weiss, Markus – PersonEntity: Name: NameFull: Wendel-Garcia, Pedro David – PersonEntity: Name: NameFull: Cannizzaro, Vincenzo – PersonEntity: Name: NameFull: Grass, Beate – PersonEntity: Name: NameFull: Buehler, Philipp Karl – PersonEntity: Name: NameFull: Kleine-Brueggeney, Maren IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: Apr2024 Type: published Y: 2024 Identifiers: – Type: issn-print Value: 13871307 Numbering: – Type: volume Value: 38 – Type: issue Value: 2 Titles: – TitleFull: Journal of Clinical Monitoring & Computing Type: main |
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