| Title: |
In‐field detection and characterization of B/Victoria lineage deletion variant viruses causing early influenza activity and an outbreak in Louisiana, 2019. |
| Authors: |
Shu, Bo, Wilson, Malania M., Keller, Matthew W., Tran, Ha, Sokol, Theresa, Lee, Grace, Rambo‐Martin, Benjamin L., Kirby, Marie K., Hassell, Norman, Haydel, Danielle, Hand, Julie, Wentworth, David E., Barnes, John R. |
| Source: |
Influenza & Other Respiratory Viruses; Jan2024, Vol. 18 Issue 1, p1-5, 5p |
| Subject Terms: |
COVID-19, INFLUENZA, VIRAL vaccines, AMINO acids, HEMAGGLUTININ, REVERSE transcriptase polymerase chain reaction |
| Geographic Terms: |
LOUISIANA, COLORADO |
| Abstract: |
Background: In 2019, the Louisiana Department of Health reported an early influenza B/Victoria (B/VIC) virus outbreak. Method: As it was an atypically large outbreak, we deployed to Louisiana to investigate it using genomics and a triplex real‐time RT‐PCR assay to detect three antigenically distinct B/VIC lineage variant viruses. Results: The investigation indicated that B/VIC V1A.3 subclade, containing a three amino acid deletion in the hemagglutinin and known to be antigenically distinct to the B/Colorado/06/2017 vaccine virus, was the most prevalent circulating virus within the specimens evaluated (86/88 in real‐time RT‐PCR). Conclusion: This work underscores the value of portable platforms for rapid, onsite pathogen characterization. [ABSTRACT FROM AUTHOR] |
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Copyright of Influenza & Other Respiratory Viruses is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| Database: |
Complementary Index |
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