Bibliographic Details
| Title: |
Mitochondrial genomes revisited: why do different lineages retain different genes? |
| Authors: |
Butenko, Anzhelika, Lukeš, Julius, Speijer, Dave, Wideman, Jeremy G. |
| Source: |
BMC Biology; 1/25/2024, Vol. 22 Issue 1, p1-16, 16p |
| Subject Terms: |
GENETIC drift, POPULATION genetics, MITOCHONDRIA, GENETIC transformation, GENES, GENOMES |
| Abstract: |
The mitochondria contain their own genome derived from an alphaproteobacterial endosymbiont. From thousands of protein-coding genes originally encoded by their ancestor, only between 1 and about 70 are encoded on extant mitochondrial genomes (mitogenomes). Thanks to a dramatically increasing number of sequenced and annotated mitogenomes a coherent picture of why some genes were lost, or relocated to the nucleus, is emerging. In this review, we describe the characteristics of mitochondria-to-nucleus gene transfer and the resulting varied content of mitogenomes across eukaryotes. We introduce a 'burst-upon-drift' model to best explain nuclear-mitochondrial population genetics with flares of transfer due to genetic drift. [ABSTRACT FROM AUTHOR] |
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| Database: |
Complementary Index |
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