Bibliographic Details
Title: |
In Vitro Studies Regarding the Effect of Cellulose Acetate-Based Composite Coatings on the Functional Properties of the Biodegradable Mg3Nd Alloys. |
Authors: |
Streza, Alexandru, Antoniac, Aurora, Veronica Manescu, Ciocoiu, Robert, Cotrut, Cosmin-Mihai, Miculescu, Marian, Miculescu, Florin, Antoniac, Iulian, Fosca, Marco, Rau, Julietta V., Dura, Horatiu |
Source: |
Biomimetics (2313-7673); Nov2023, Vol. 8 Issue 7, p526, 22p |
Subject Terms: |
COMPOSITE coating, RARE earth metals, METALLIC composites, ALLOYS, MAGNESIUM alloys, CELLULOSE acetate, ORTHOPEDIC implants |
Abstract: |
Magnesium (Mg) alloys are adequate materials for orthopedic and maxilo-facial implants due to their biocompatibility, good mechanical properties closely related to the hard tissues, and processability. Their main drawbacks are the high-speed corrosion process and hydrogen release. In order to improve corrosion and mechanical properties, the Mg matrix can be strengthened through alloying elements with high temperature-dependent solubility materials. Rare earth elements (RE) contribute to mechanical properties and degradation improvement. Another possibility to reduce the corrosion rate of Mg-based alloys was demonstrated to be the different types of coatings (bioceramics, polymers, and composites) applied on their surface. The present investigation is related to the coating of two Mg-based alloys from the system Mg3Nd (Mg-Nd-Y-Zr-Zn) with polymeric-based composite coatings made from cellulose acetate (CA) combined with two fillers, respectively hydroxyapatite (HAp) and Mg particles. The main functions of the coatings are to reduce the biodegradation rate and to modify the surface properties in order to increase osteointegration. Firstly, the microstructural features of the experimental Mg3Nd alloys were revealed by optical microscopy and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy. Apart from the surface morphology revealed by SEM, the roughness and wettability of all experimental samples were evaluated. The corrosion behavior of the uncoated and coated samples of both Mg3Nd alloys was investigated by immersion testing and electrochemical testing using Simulated Body Fluid as the medium. The complex in vitro research performed highlights that the composite coating based on CA with HAp particles exhibited the best protective effect for both Mg3Nd alloys. [ABSTRACT FROM AUTHOR] |
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Database: |
Complementary Index |