Bibliographic Details
Title: |
Long-term health-related quality of life in survivors of severe acute pancreatitis. |
Authors: |
Halonen, Kimmo I., Pettilä, Ville, Leppäniemi, Ari K., Kemppainen, Esko A., Puolakkainen, Pauli A., Haapiainen, Reijo K., Pettilä, Ville, Leppäniemi, Ari K |
Source: |
Intensive Care Medicine; May2003, Vol. 29 Issue 5, p782-786, 5p |
Subject Terms: |
DIABETES complications, PANCREATITIS, HOSPITAL wards, CRITICAL care medicine, INTENSIVE care units, ENDOCRINE diseases, PANCREATITIS treatment, PROGNOSIS, QUALITY of life, QUESTIONNAIRES, SURVIVAL analysis (Biometry), RETROSPECTIVE studies, SEVERITY of illness index, ACUTE diseases |
Geographic Terms: |
FINLAND |
Abstract: |
Objective: To evaluate the health-related quality of life (HRQL) and postdischarge outcome after severe acute pancreatitis.Design and Setting: Observational study in a department of surgery (surgical and general intensive care unit) in a tertiary care hospital.Patients and Participants: Of 283 patients with severe acute pancreatitis 211 survived; during a follow-up period an additional 27 died. The Rand 36-item Health Survey with accessory question was mailed to 174 eligible patients. The final study population comprised 145 patients (83% response rate). Age- and sex-matched Finnish population scores were compared with the study population; accessory questions were analyzed separately.Results: No clinically significant differences were found in long-term HRQL between study patients and the general population. Of the 145 patients 87% returned to work, 27% suffered recurrent pancreatitis, and 43% developed diabetes. Of 113 patients with alcohol-induced severe acute pancreatitis 30% were abstinent and 28% problem drinkers, alcohol-dependent, or alcoholics.Conclusions: Up to 13% of severe acute pancreatitis patients surviving initial hospitalization die within a few years. Among the survivors long-term HRQL is comparable to that of the normal population. The majority return to work and reduce their alcohol consumption markedly. [ABSTRACT FROM AUTHOR] |
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Database: |
Complementary Index |